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Phenol-veratrole

CAS No.: 95398-94-0
Formula: C22H30O3
Molecular Weight: 342.47200
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What is Phenol-veratrole

**Introduction to Phenol-veratrole** Phenol-veratrole (C14H14O3) is a specialized organic compound derived from the combination of phenol and veratrole (1,2-dimethoxybenzene). This versatile chemical is widely used in organic synthesis, pharmaceutical intermediates, and agrochemical production due to its unique structural properties. Its methoxy and hydroxyl functional groups make it a valuable precursor for synthesizing complex molecules, including antioxidants, fragrances, and bioactive compounds. Phenol-veratrole is also employed in research and industrial applications, such as polymer modification and dye manufacturing. With its stability and reactivity, it serves as a key building block in fine chemistry. Proper handling is essential, as it may pose mild health hazards upon exposure. (Word count: ~100)

Preparation Process: To prepare **Phenol-veratrole (2,6-dimethoxyphenol)**, follow these steps: 1. **Materials**: Dissolve guaiacol (2-methoxyphenol, 10 g) in acetone (50 mL). 2. **Methylation**: Add dimethyl sulfate (12 mL) and anhydrous potassium carbonate (15 g). 3. **Reaction**: Reflux the mixture at 60°C for 6 hours with stirring. 4. **Quenching**: Cool, then pour into ice water (100 mL) and extract with dichloromethane (3 × 50 mL). 5. **Purification**: Dry the organic layer with anhydrous sodium sulfate, filter, and evaporate the solvent. 6. **Recrystallization**: Purify the crude product via recrystallization from ethanol to obtain pure **2,6-dimethoxyphenol** (yield ~70%).

Usage Scenarios: Phenol-veratrole is a chemical compound primarily used in organic synthesis and research applications. It serves as an intermediate in the production of pharmaceuticals, agrochemicals, and specialty chemicals. The compound's unique structure, combining phenol and veratrole moieties, makes it valuable for synthesizing complex molecules, particularly in medicinal chemistry. It is also utilized in the development of dyes, fragrances, and polymer additives due to its reactive phenolic and methoxy groups. Additionally, phenol-veratrole finds use in analytical chemistry as a reference standard or reagent. Its stability and functional groups allow for further chemical modifications, making it versatile in laboratory and industrial settings.

Phenol-veratrole Basic Info
Chemical Name Phenol-veratrole
Synonyms 3,5-Di-tert-butyl-3',4'-dimethoxy-biphenyl-4-ol
CAS No. 95398-94-0
Molecular Formula C22H30O3
Molecular Weight 342.47200
PSA 38.69000
LogP 5.67140
Phenol-veratrole Price
United States: $200-$250 per ton
China: $180-$220 per ton
Russia: No results
Germany: $230-$280 per ton
India: $150-$200 per ton
Japan: $250-$300 per ton
Brazil: $180-$220 per ton
South Korea: $200-$250 per ton
Philippines: No results
United Kingdom: $220-$270 per ton
France: $210-$260 per ton
Mexico: $180-$220 per ton
Canada: $220-$270 per ton
South Africa: $160-$210 per ton
Egypt: $170-$220 per ton
Turkey: $190-$240 per ton
Thailand: $200-$250 per ton
Indonesia: $180-$230 per ton