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caffeine-sodium benzoate

CAS No.: 82783-24-2
Formula: C15H16N4NaO4
Molecular Weight: 339.30200
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What is caffeine-sodium benzoate

**Introduction to Caffeine-Sodium Benzoate** Caffeine-sodium benzoate is a water-soluble compound combining caffeine with sodium benzoate, enhancing its absorption and bioavailability. Primarily used as a central nervous system stimulant, it helps combat fatigue, improve alertness, and boost cognitive performance. This formulation is commonly found in injectable medications for rapid effects in treating conditions like migraines, respiratory depression, or hypotension. It is also used in some energy supplements and pharmaceuticals due to its quick-acting properties. While effective, proper dosing is essential to avoid side effects such as jitteriness, insomnia, or increased heart rate. Always consult a healthcare professional before use to ensure safety and efficacy.

Preparation Process: Caffeine-sodium benzoate is prepared by combining caffeine and sodium benzoate in a 1:1 molar ratio. Dissolve caffeine in hot water (60-70°C) and add an equimolar amount of sodium benzoate with stirring until fully dissolved. Filter the solution to remove impurities, then cool to room temperature for crystallization. Alternatively, evaporate the solvent under reduced pressure to obtain the solid product. Wash the crystals with cold water or ethanol to remove residual reactants, then dry at 50-60°C. The product is a white crystalline powder, soluble in water, and used as a stimulant in pharmaceutical formulations. Ensure proper stoichiometry and purification for high purity.

Usage Scenarios: Caffeine-sodium benzoate is a combination of caffeine and sodium benzoate, primarily used as a central nervous system stimulant. It enhances alertness, reduces fatigue, and improves concentration by blocking adenosine receptors. Medically, it is administered intravenously to treat conditions like apnea in premature infants, headaches, and hypotension. The sodium benzoate component increases caffeine's solubility, allowing faster absorption. It is also used in emergency settings for acute caffeine toxicity management. Additionally, it may be included in some analgesic formulations to boost pain relief. The compound is sometimes utilized in sports and military contexts to sustain physical and mental performance under fatigue.

caffeine-sodium benzoate Basic Info
Chemical Name caffeine-sodium benzoate
Synonyms -
CAS No. 82783-24-2
Molecular Formula C15H16N4NaO4
Molecular Weight 339.30200
PSA 99.12000
LogP 0.35550
caffeine-sodium benzoate Price
United States: $10 - $50 per kg
China: $5 - $20 per kg
Russia: $8 - $30 per kg
Germany: $15 - $40 per kg
India: $4 - $15 per kg
Japan: $20 - $50 per kg
Brazil: $10 - $25 per kg
South Korea: $15 - $35 per kg
Philippines: $5 - $20 per kg
United Kingdom: $12 - $35 per kg
France: $15 - $40 per kg
Mexico: $8 - $25 per kg
Canada: $10 - $30 per kg
South Africa: $7 - $20 per kg
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Turkey: $10 - $30 per kg
Thailand: $5 - $18 per kg
Indonesia: $4 - $15 per kg