(S)-(-)-LIMONENE C10H16 Properties,Formula,Price, Uses

What is (S)-(-)-LIMONENE

(4S)-Limonene is a naturally occurring monoterpene found in the essential oils of citrus fruits, particularly in the peels of oranges, lemons, and limes. Known for its fresh, citrusy aroma, it is widely used in the food, fragrance, and cleaning industries as a flavoring agent, fragrance additive, and natural solvent. (4S)-Limonene is the S-enantiomer of limonene, distinguished by its specific molecular configuration, which contributes to its unique properties. Beyond its industrial applications, it has gained attention for its potential health benefits, including antioxidant, anti-inflammatory, and anticancer properties. As a sustainable and renewable resource, (4S)-limonene is a versatile compound with growing importance in green chemistry and eco-friendly product development.

Preparation Process: (4S)-Limonene can be prepared through the fractional distillation of citrus peel oils, primarily from oranges, which naturally contain high concentrations of (4S)-limonene. The process involves steam distillation of citrus peels to extract the essential oil, followed by fractional distillation under reduced pressure to isolate (4S)-limonene with high purity. Alternatively, enantioselective synthesis can be achieved via asymmetric hydrogenation of myrcene using a chiral catalyst, such as a rhodium complex with (R)-BINAP, to favor the (4S)-enantiomer. Another method involves the enzymatic resolution of racemic limonene using lipases to selectively hydrolyze the (4R)-enantiomer, leaving (4S)-limonene enriched. Purification is typically performed via column chromatography.

Usage Scenarios: (4S)-Limonene, a monoterpene found in citrus peels, is widely used in the food, fragrance, and pharmaceutical industries. As a flavoring agent, it imparts a citrusy aroma to foods and beverages. In perfumery, it serves as a natural solvent and fragrance enhancer. Industrially, it acts as a biodegradable cleaning agent and degreaser. In pharmaceuticals, (4S)-limonene exhibits potential therapeutic effects, including anti-inflammatory, antioxidant, and anticancer properties. It is also studied for its role in drug delivery systems due to its lipophilic nature. Additionally, it serves as a precursor in the synthesis of other valuable compounds, such as carvone and menthol.

(S)-(-)-LIMONENE Basic Info

Chemical Name (S)-(-)-LIMONENE

Synonyms L-LIMONENE;(-)-Limonene;(S)-1-Methyl-4-(prop-1-en-2-yl)cyclohex-1-ene;beta-limonene;(s)-(-)-p-mentha-8-diene;(-)-1,8-p-menthadiene,(S)-(-)-limonene;(S)-(-)-4-ISOPROPENYL-1-METHYL-1-CYCLOHEXENE;1-methyl-4-(1-methylethenyl)-,(S)-Cyclohexene;cyclohexene,1-methyl-4-(1-methylethenyl)-,(S)-;LIMONENER

CAS No. 5989-54-8

Molecular Formula C10H16

Molecular Weight 136.23

PSA 0.00000

LogP 4.38 at 37℃

Safely Info

RTECS OS8350000

Hazard Class 3

Safety Statements 24-37-60-61

HS Code 29029090

WGK Germany -

Packing Group III

RIDADR UN 2052 3/PG 3

Risk Statements 10-38-43-50/53

Hazard Codes Xi,N

Caution Statement P210-P273-P280-P301+P310+P331-P302+P352

Hazard Declaration H226-H304-H317-H400

Symbol GHS02,GHS07,GHS08,GHS09

Signal Word Danger

(S)-(-)-LIMONENE Price

United States: $10-20
China: $5-15
Russia: $8-18
Germany: $15-25
India: $3-8
Japan: $20-30
Brazil: $7-17
South Korea: $12-22
Philippines: $5-10
United Kingdom: $15-25
France: $18-28
Mexico: $6-16
Canada: $10-20
South Africa: $9-19
Egypt: $6-12
Turkey: $7-17
Thailand: $5-10
Indonesia: $4-9

MSDS

Name:	(-)-Limonene 92% Material Safety Data Sheet
Synonym:	(S)-Limonene; l-Limonene
CAS:	5989-54-8

Section 1 - Chemical Product MSDS Name:(-)-Limonene 92% Material Safety Data Sheet
Synonym:(S)-Limonene; l-Limonene

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
5989-54-8	(-)-Limonene	92	227-815-6

Hazard Symbols: XI N
Risk Phrases: 10 38 43 50/53

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Flammable. Irritating to skin. May cause sensitization by skin contact. Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May cause an allergic reaction in certain individuals.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Vapors may cause dizziness or suffocation.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical aid.
Skin:
In case of contact, immediately flush skin with soap and plenty of water. Remove contaminated clothing and shoes. Get medical aid if symptoms occur. Wash clothing before reuse.
Ingestion:
If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation:
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air.
During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas.
Extinguishing Media:
For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective. Do NOT use straight streams of water.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. A vapor suppressing foam may be used to reduce vapors.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Keep away from heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Flammables-area.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 5989-54-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Liquid
Color: clear, colorless
Odor: citrus-like odor
pH: Not available.
Vapor Pressure: 1.44 mm Hg @ 25 deg C
Viscosity: Not available.
Boiling Point: 175-177 deg C @ 760 mmHg
Freezing/Melting Point: -74 deg C
Autoignition Temperature: 255 deg C ( 491.00 deg F)
Flash Point: 48 deg C ( 118.40 deg F)
Explosion Limits, lower: .70 vol %
Explosion Limits, upper: 6.10 vol %
Decomposition Temperature:
Solubility in water: practically insoluble
Specific Gravity/Density: .8420 g/cm3
Molecular Formula: C10H16
Molecular Weight: 136.24

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Ignition sources, excess heat.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 5989-54-8: OS8350000 LD50/LC50:
CAS# 5989-54-8: Draize test, rabbit, skin: 500 mg/24H Moderate.
Carcinogenicity:
(-)-Limonene - Not listed by ACGIH, IARC, or NTP.
Other:
See actual entry in RTECS for complete information.

Section 12 - ECOLOGICAL INFORMATION
Other No information available.

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Dipentene
Hazard Class: 3
UN Number: 2052
Packing Group: III
IMO
Shipping Name: Dipentene
Hazard Class: 3.3
UN Number: 2052
Packing Group: III
RID/ADR
Shipping Name: Dipentene
Hazard Class: 3
UN Number: 2052
Packing group: III

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI N
Risk Phrases:
R 10 Flammable.
R 38 Irritating to skin.
R 43 May cause sensitization by skin contact.
R 50/53 Very toxic to aquatic organisms, may cause
long-term adverse effects in the aquatic environment.
Safety Phrases:
S 24 Avoid contact with skin.
S 37 Wear suitable gloves.
S 60 This material and its container must be
disposed of as hazardous waste.
S 61 Avoid release to the environment. Refer to
special instructions/safety data sheets.
WGK (Water Danger/Protection)
CAS# 5989-54-8: 1
Canada
CAS# 5989-54-8 is listed on Canada's DSL List.
CAS# 5989-54-8 is listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 5989-54-8 is listed on the TSCA inventory.

SECTION 16 - ADDITIONAL INFORMATION
N/A

Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search

1.Identification

1.1 GHS Product identifier

Product name	(4S)-limonene

1.2 Other means of identification

Product number	-
Other names	(4S)-1-methyl-4-prop-1-en-2-ylcyclohexene

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only. Food additives -> Flavoring Agents
Uses advised against	no data available

1.4 Supplier's details

Company	MOLBASE (Shanghai) Biotechnology Co., Ltd.
Address	Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road, Xuhui District, Shanghai, China
Telephone	+86(21)64956998
Fax	+86(21)54365166

1.5 Emergency phone number

Emergency phone number	+86-400-6021-666
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Flammable liquids, Category 3

Skin irritation, Category 2

Skin sensitization, Category 1

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H226 Flammable liquid and vapour H315 Causes skin irritation H317 May cause an allergic skin reaction H410 Very toxic to aquatic life with long lasting effects
Precautionary statement(s)
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection. P264 Wash ... thoroughly after handling. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P273 Avoid release to the environment.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P391 Collect spillage.
Storage	P403+P235 Store in a well-ventilated place. Keep cool.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name	Common names and synonyms	CAS number	EC number	Concentration
(4S)-limonene	(4S)-limonene	5989-54-8	none	100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state	colourless liquid with lemon odour
Colour	no data available
Odour	no data available
Melting point/ freezing point	250°C(dec.)(lit.)
Boiling point or initial boiling point and boiling range	64°C/15mmHg(lit.)
Flammability	no data available
Lower and upper explosion limit / flammability limit	no data available
Flash point	45°C(lit.)
Auto-ignition temperature	no data available
Decomposition temperature	no data available
pH	no data available
Kinematic viscosity	no data available
Solubility	no data available
Partition coefficient n-octanol/water (log value)	4.38
Vapour pressure	no data available
Density and/or relative density	0.842
Relative vapour density	no data available
Particle characteristics	no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

Oral: no data available
Inhalation: no data available
Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

Toxicity to fish: no data available
Toxicity to daphnia and other aquatic invertebrates: no data available
Toxicity to algae: no data available
Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2319

IMDG: UN2319

IATA: UN2319

14.2 UN Proper Shipping Name

ADR/RID: TERPENE HYDROCARBONS, N.O.S.

IMDG: TERPENE HYDROCARBONS, N.O.S.

IATA: TERPENE HYDROCARBONS, N.O.S.

14.3 Transport hazard class(es)

ADR/RID: 3

IMDG: 3

IATA: 3

14.4 Packing group, if applicable

ADR/RID: III

IMDG: III

IATA: III

14.5 Environmental hazards

ADR/RID: yes

IMDG: yes

IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name	Common names and synonyms	CAS number	EC number
(4S)-limonene	(4S)-limonene	5989-54-8	none
European Inventory of Existing Commercial Chemical Substances (EINECS)			Listed.
EC Inventory			Listed.
United States Toxic Substances Control Act (TSCA) Inventory			Listed.
China Catalog of Hazardous chemicals 2015			Not Listed.
New Zealand Inventory of Chemicals (NZIoC)			Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS)			Listed.
Vietnam National Chemical Inventory			Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC)			Listed.

16.Other information

Information on revision

Creation Date	Aug 12, 2017
Revision Date	Aug 12, 2017

Abbreviations and acronyms

CAS: Chemical Abstracts Service
ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
IMDG: International Maritime Dangerous Goods
IATA: International Air Transportation Association
TWA: Time Weighted Average
STEL: Short term exposure limit
LC50: Lethal Concentration 50%
LD50: Lethal Dose 50%
EC50: Effective Concentration 50%

References

IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

(S)-(-)-LIMONENE Products
Total12 Products

(S)-(-)-LIMONENE Suppliers

Company Name

Business Type

Location

Details

LEAP CHEM CO., LTD.

China

Request For Quotation

PRIVI Organics Ltd.

美国

Request For Quotation

(S)-(-)-LIMONENE

What is (S)-(-)-LIMONENE

(S)-(-)-LIMONENE Basic Info

Safely Info

(S)-(-)-LIMONENE Price

MSDS

(S)-(-)-LIMONENE Products Total12 Products

(S)-(-)-LIMONENE Suppliers

Hot Recommendation

(S)-(-)-LIMONENE Products
Total12 Products