2-Hpymo*HNO3

What is 2-Hpymo*HNO3

**Introduction to 2-Hydroxypyrimidine Mononitrate (2-HPYMO·HNO₃)** 2-Hydroxypyrimidine Mononitrate (2-HPYMO·HNO₃) is a specialized organic compound combining the hydroxypyrimidine moiety with nitric acid, forming a stable nitrate salt. This crystalline solid is notable for its potential applications in pharmaceuticals, agrochemicals, and material science. The pyrimidine core, a key heterocyclic structure, lends itself to biological activity, making 2-HPYMO·HNO₃ a candidate for drug development, particularly in antimicrobial or antiviral formulations. Its nitrate component may enhance solubility and bioavailability. Additionally, it serves as a versatile intermediate in synthetic chemistry for constructing complex molecules. With balanced reactivity and stability, 2-HPYMO·HNO₃ offers a valuable tool for researchers and industries seeking innovative solutions in fine chemical synthesis. (*100 words*)

Preparation Process: To prepare **2-Hpymo·HNO₃**, dissolve **2-hydroxypyrimidine (2-Hpymo)** in a minimal amount of warm ethanol. Gradually add **concentrated nitric acid (HNO₃)** in a 1:1 molar ratio under stirring at room temperature. A white precipitate forms immediately. Filter the product, wash with cold ethanol to remove excess acid, and dry under vacuum. Alternatively, evaporate the solvent slowly to obtain crystals. The compound can be recrystallized from a mixture of ethanol and water for higher purity. Confirm the structure via elemental analysis, IR spectroscopy, or X-ray diffraction. Handle HNO₃ with care due to its corrosive nature.

Usage Scenarios: The compound **2-Hpymo·HNO₃** (2-hydroxypyrimidine nitrate) is primarily utilized in coordination chemistry and materials science. It serves as a versatile ligand for synthesizing metal-organic frameworks (MOFs) and coordination polymers due to its ability to bind metal ions through its hydroxyl and nitrogen sites. The nitrate counterion enhances solubility and influences crystal packing. Applications include catalysis, gas storage, and molecular sensing. Its structural flexibility allows for tuning material properties, making it useful in designing functional materials. Additionally, it may find use in pharmaceutical research as a precursor for bioactive molecules or in supramolecular chemistry for constructing hydrogen-bonded networks.

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