INSULIN LISPRO (5.97 MG)

What is INSULIN LISPRO (5.97 MG)

**Introduction to Insulin Lispro (5.97 mg)** Insulin Lispro (5.97 mg) is a rapid-acting insulin analog designed to mimic the body's natural insulin response, providing fast blood sugar control after meals. With a quick onset (15–30 minutes) and short duration (3–5 hours), it is ideal for managing postprandial glucose spikes in individuals with diabetes. Its modified molecular structure allows for faster absorption compared to regular human insulin, improving convenience and flexibility in dosing. This formulation is commonly used in insulin pumps or as part of basal-bolus therapy. Available in vials or prefilled pens, Insulin Lispro (5.97 mg) offers precise dosing and reliable glycemic control, enhancing quality of life for patients with type 1 or type 2 diabetes. (Word count: ~100)

Preparation Process: **Preparation Method of Insulin Lispro (5.97 mg):** 1. **Recombinant DNA Technology:** Insulin lispro is produced using genetically modified *Escherichia coli* or yeast cells expressing the modified human insulin gene. 2. **Fermentation:** The host cells are cultured in a controlled bioreactor under optimized conditions (pH, temperature, nutrients) to produce the insulin lispro precursor. 3. **Purification:** The precursor is isolated via centrifugation, filtration, and chromatography (e.g., reverse-phase HPLC) to remove impurities. 4. **Enzymatic Cleavage:** Specific enzymes cleave the precursor to yield insulin lispro. 5. **Formulation:** The purified insulin lispro (5.97 mg) is dissolved in a sterile buffer (e.g., phosphate or citrate) with preservatives (e.g., m-cresol) and zinc for stability. 6. **Sterile Filtration & Packaging:** The solution is filtered (0.22 µm) and aseptically filled into vials or cartridges.

Usage Scenarios: Insulin lispro (5.97 mg) is a rapid-acting synthetic insulin analog used to manage blood glucose levels in individuals with diabetes mellitus. It mimics the body's natural insulin response, with a faster onset (15–30 minutes) and shorter duration (3–5 hours) compared to regular human insulin. This makes it ideal for controlling postprandial hyperglycemia when administered just before or immediately after meals. It is commonly prescribed for type 1 diabetes and sometimes for type 2 diabetes, often in combination with long-acting insulin. Insulin lispro improves glycemic control, reduces hypoglycemia risk, and offers flexibility in dosing, enhancing patient adherence and quality of life.

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